Controlling stealth and barrier breaking behavior: Hybrid protein nanofibers and POxylation on polymeric nanoparticles with structurally tailored thermal properties
A chemist works in the synthesis lab.
By modulating the surface of polyester nanoparticles with poly(2-oxazoline)s (POx) and hybrid protein nanofibers (HPNF), the project will investigate the influence of these attached materials on the internal structure of the nanoparticle core through assessment of the thermal and mechanical properties. Depending on their structure and functionality, the POx and HPNF will also induce stealth or barrier breaking properties of the nanoparticles and serve as platform for the attachment of targeting ligands.
Prof. Dr. Ulrich S. Schubert
Laboratory of Organic and Macromolecular Chemistry (IOMC)
Friedrich Schiller University Jena
Humboldtstraße 10
07743 Jena
Phone: +49 3641 9-48200
ulrich.schubert@uni-jena.de