C04
C04 investigates the internalisation of nanoparticles into cells and tissue and their association to intracellular compartments and their interactions with membranes. For this purpose, a combination of electron microscopy and high-resolution fluorescence microscopy techniques are utilised. Co-localisation of inflammatory markers, enzymes and receptors in the cellular context in response of particle uptake and drug release is used to obtain a deeper inside into the mode of action of nanoparticle formulations in the biological context.
graphical abstract C04
Image: S. HoeppenerPrinciple investigators
PD. Dr. Stephanie Höppener
Image: Anne Günther (University of Jena)PD. Dr. Stephanie Höppener
Electron Microscopy Group (EMG)
Jena Center for Soft Matter (JCSM)
Friedrich Schiller Unviversity Jena
Philosophenweg 7
07743 Jena
Phone: +49 3641 9-48596
s.hoeppener@uni-jena.de
Prof. Dr. Rainer Heintzmann
Image: Prof. Dr. Rainer HeintzmannProf. Dr. Rainer Heintzmann
Institute for Physical Chemistry (IPC)
Friedrich Schiller Unviversity Jena
Helmholtzweg 4
07745 Jena
Phone: +49 3641 9-48350
rainer.heintzmann@uni-jena.de
Staff
Hossein Zarei Oshtolagh
Institute of Physical Chemistry (IPC)
Helmholtzweg 4
07745 Jena
Phone:
zareioshtolagh@uni-jena.de